Christina Applegate

CHRISTINA APPLEGATE has endeared herself to audiences and received accolades for her strength and versatility in theatre, film and television. She starred as the voice of Brittany, the lead Chipette, in the blockbuster "Alvin and the Chipmunks: The Squeakquel"; she was seen on the big screen in the Farrelly brothers' comedy "Hall Pass," with Owen Wilson, Jason Sudeikis and Jenna Fischer, and the romantic comedy "Going the Distance," with Drew Barrymore and Justin Long.

Her performance as the title character in the hit ABC series "Samantha Who?" has garnered two Emmy Award nominations for Applegate, as well as three SAG Award® nominations, two Golden Globe Award nominations, a Satellite Award nomination and a Prism Award nomination. In addition, Applegate served as a producer on the show, which won a People's choice Award for Favorite New Comedy during its first season.

Applegate's film credits include "The Rocker," for director Peter Cattaneo, in which she stared opposite Rainn Wilson; "Surviving Christmas," for director Mike Mitchell; the comedy "Anchorman: The Legend of Ron Burgundy," with Will Farrell; her critically praised performance alongside Cameron Diaz and Selma Blair in the raucous comedy "The Sweetest Thing"; "Wonderland"; "View From the Top," with Gwyneth Paltrow; and Stephen Herek's "Don't Tell Mom the Babysitter's Dead."

Applegate first gained widespread attention as the sexy and sarcastic Kelly Bundy on the series "Married with Children." After its very successful 11-season run, she furthered her television success by starring in her own NBC comedy, "Jesse." In 1999, the highly rated show earned Applegate a People's Choice Award and a Golden Globe Award nomination. In 2004, she returned to television as a guest star on "Friends," as Rachel's younger sister, Amy, winning an Emmy Award for her witty performance and a subsequent nomination the following year.

In 2005, she earned a Tony Award nomination and a Drama Desk Award for her Broadway debut as Charity Hope Valentine in the revival of "Sweet Charity." Her other stage credits include an appearance in John Cassavetes' Los Angeles production of "The Third Day," with Gena Rowlands, "The Axeman's Jazz," "Nobody Leaves Empty Handed," "The Run-Through" and "The Grass Harp."

In 2008, after receiving her breast cancer diagnosis through an early, doctor-ordered MRI, Applegate founded Right Action for Women to educate women about what it means to be at high risk for breast cancer and encourage them to talk to their doctors about appropriate screening. Right Action for Women provides aid to individuals at increased risk for breast cancer who do not have insurance or the financial flexibility to cover the high costs associated with screenings. A longtime supporter of women's cancer causes, Applegate served in 2003 and 2009 as the ambassador for Lee National Denim Day, one of the largest single-day fundraisers for breast cancer in the country.

TM & © 2010 Warner Bros. Entertainment Inc